HAIR PREMIUM

Taurine, a nutrient that protects the hair bulb. The hair bulb is where the hair is produced, in depth, and is the most vascularized area to allow the arrival of nutrients. In hair loss an alteration occurs in the same which causes deformation of the sheath surrounding the bulb and a drop of the microcirculation which transports nutrients thus reducing hair mass. Contains sulphur which helps in hair growth, quality and texture and helps in building collagen to promote scalp surface.

 

Black currant seed oil rich in omega 6 (GLA) and Omega 3 (ALA), Inhibit the action of the enzyme, 5-alpha reductase to help balance hormone levels and support healthy hair growth.

Considering the main importance of skin over hair growth it softens and protects the skin. Contains significant amounts of linolenic acid and gamma-linolenic acid (GLA). Linolenic acid (ALA) is one of the most important fatty acids in ceramides which are the largest class of polar lipids of the stratum corneum. Its deficiency leads to altered lipid bilayers stacked around the corneocytes layer resulting in an impairment of the barrier function, involves scaling and thickening of the epidermis, accompanied by a greater loss of water from the epidermis (sign of epidermal barrier disruption). The GLA is rapidly and efficiently converted in dihomo-y-linolenic, precursor of metabolites with potent anti-inflammatory effects. Its deficit may predispose to inflammatory skin overreactions. GLA consumption normalizes inflammatory eicosanoids balance. Therefore deficiency of linolenic acid and GLA can not only alter the skin barrier but predispose skin to inflammatory overreactions.

 

Zinc is an essential cofactor for multiple enzymes, essential nutrient for the hair, and it is involved with important functional activities in the hair follicle. Further, zinc is a potent inhibitor of hair follicle regression and it accelerates hair follicle recovery, it is essential for keratine production (protein that gives structure to our hair). Helps to slow down hair loss.

 

Green Tea Extract is an excellent source of potent polyphenols (bioflavonoids with powerful antioxidant properties). Research has identified EGCG as the most active polyphenolic compound in Green Tea that improves microcirculation and allows nutrient reach the hair bulb. Inhibit the action of the enzyme, 5-alpha reductase to help balance hormone levels and support healthy hair growth.

 

Grape seed extract Oligomeric Proanthocyanidins (OPC), antioxidant that protects against free radicals and oxidative stress that not only provide cardiovascular support but also support scalp circulation and as antioxidants, help to protect hair follicles. Research indicates that PCOs support growth of hair epithelial cells and hair follicle cell growth.

 

L-methionine, is an essential amino acid very important for hair and for the manufacture of keratin, which give hair its tensile strength. Is a sources of sulphur, key to support hair quality, texture and growth and aid in the production of collagen to support the surface of the scalp. He is also a precursor of taurine (hair bulb guard) and glutathione (an important antioxidant). It is one of the amino acid more susceptible to be damaged and oxidized by free radicals (ROS) which alters the protein structure and lead to the loss of function, which is toxic to cells. It can be oxidized to methionine sulfoxide (MetSO). The absence of methionine is detrimental to growth and hair formation and also negative for the formation of taurine (protects hair bulb) and glutathione (a major antioxidant in the body).

According to recent researches, human grey/white scalp hair shafts accumulate hydrogen peroxide (H2O2) in millimolar concentrations (Reactive Oxigen Specie that attacks our body and hair). Moreover, they demonstrate almost absent catalase (enzyme that deactivates hydrogen peroxide ROS which has been deactivated by hydrogen peroxide itself) and methionine sulfoxide reductase A and B protein expression (responsible for MEt-S O repair and both deactivated by hydrogen peroxide) in association with a functional loss of methionine sulfoxide (Met-S_O) repair in the entire gray hair follicle. Accordingly, Met-S_O formation of Met residues, which includes MEt374, in the active site of tyrosinase, the key enzyme in melanogenesis, limits enzyme functionality, which leads to gradual loss of hair color. Free l-methionine can prevent Met-S_O formation of protein- and peptide-bound Met residues, allowing tyrosinase activity and saving in turn protein integrity and function, which could have great implications in the hair greying scenario in humans.

 

Catalase, fights greying, is an antioxidant enzyme that scavenges free radicals. It scavenges hydrogen peroxide which is dangerous and responsible for graying hair. According to recent researches, human grey/white scalp hair shafts accumulate hydrogen peroxide (H2O2) in millimolar concentrations. Moreover, they demonstrate almost absent catalase and methionine sulfoxide reductase A and B protein expression (responsable for MEt-S O repair and both deactivated by hydrogen peroxide) in association with a functional loss of methionine sulfoxide (Met-S_O) repair in the entire gray hair follicle. Accordingly, Met-S_O formation of Met residues, which includes MEt374, in the active site of tyrosinase, the key enzyme in melanogenesis, limits enzyme functionality, which leads to gradual loss of hair colour. Catalase destroys hydrogen peroxide in the hair follicle protecting it and allowing the action of other enzymes of the body's defence and tyrosinase, allowing transfer of melanin to the hair roots, and avoiding or delaying the graying.